Terms & Conditions | F.A.Q.

  Your Cart:


Your Cart is empty


Home Checkout My Cart Contact us
My account

You are currently not loggged in.
Login     Register

See Our offers:
Bulking Steroids:
Anabol 10mg x 100 tablets
Anabol 10mg x 1000 tablets
Anabol 5mg x 1000 tablets
Anabol 5mg x 1000 Tabs
Anabol 50 50mg x 100 tablets
Anabol 50mg, C&K, China 50mg x 100 tablets
Anabol 5mg x 1000 tablets
Anabol, 5mg - C&K 5mg x 100 tablets
Anadrol 50 50mg x 100 tablets
Anapolon 50mg 50mg x 20 tablets
Anavar 5mg x 30 tablets
Anazol 2mg x 100 tablets
Andriol 40mg x 20 capsules
Andriol Testocaps 40mg x 60 capsules
Andriol Testocaps 40mg x 60 capsules
Andriol Testocaps 40mg x 60 capsules
Androgel / Cernos Gel 1% 5gms x 14 pouches
Androlic 100 tablets x 50mg
Androlic British Dragon 20 tablets x 50mg
Androlic 50mg 100 tablets x 50mg
Andropen 275 Testosterone blend 1 vial x 10ml, 275mg per 1ml
Andropen 275 Testosterone blend 2 vials x 10ml, 275mg per 1ml
Androvit Depot 1 vial x 5 ml, 250mg per 1ml
Averbol 25 1 vial x 10 ml, 25mg per 1ml
Azolol 5mg x 400 tablets
BONALONE 50mg x 100 tablets
Clomid 50mg 50mg x 50 tablets
Cypioject 1 vial x 10ml (200 mg/ml)
Cypionator 300 1 vial x 10ml (300 mg/ml)
Cypionax 200 10 ampules x 2ml (200 mg/2ml)
Cytopilin-200 1 vial x 10ml (200 mg/ml)
Danabol 10mg x 500 tablets
Danabol 10mg x 500 tablets
Deca Durabolin 1 ampule x 1ml, 100mg/ml
Deca Norma 1 vial x 2ml, 200mg/2ml
Deca Durabolin 5 vials x 2ml / 100mg/1ml
Deca-durabolin 1 ampule x 1ml, 100mg/ml
Deca-durabolin 50mg 1 ampule x 1ml, 50mg/ml
Decabol 250 1 ampule x 1ml, 50mg/ml
Decabole 300 1 vial x 10ml, 300mg in 1 ml
Decadubol-100 3 vials x 2ml, 100mg/ml
Decaject 200 1 vial x 10ml, 200mg/ml
Dinandrol 3 vials x 2ml, 100mg/ml
Durabol 100 1 vial x 10ml, 100mg per ml
Durabol 200 1 vial x 10ml, 200mg per ml
Durabole 200 1 vial x 10ml, 200mg per ml
Durabolin 25 3 ampules x 1ml, 25mg/1ml
Halotestex 10mg x 50 tablets
Halotestin 10mg x 100 tablets
Mastabol Depot 200 1 vial x 10ml, 200mg/ml
Metanabol 5mg x 20 tablets
Methanabol 10mg x 100 tablets
Methanabol 10mg x 500 tablets
Methanabol 50 50mg x 100 tablets
Methandriol Dipropionate 75 1 vial x 10ml, 75mg per ml
Methandrostenolon 100 tablets x 5mg
Nandrolone decanoate 2ml 1 vial x 2ml, 100mg/ml
Naposim (Dianabol/Methandianone) 5mg x 20 tablets
Naposim 5mg 5mg x 200 tablets
Omnadren 250mg 5 ampules x 1ml, 250mg/ml
Oxanabol 10mg x 50 tablets
Oxanabol 5mg 5mg x 100 tablets
Oxandrolone 50 Tabs/5mg 5mg x 50 tablets
Oxandrolone SPA 2.5mg 2.5mg x 30 tablets
Oxydrol 50 50mg x 100 tablets
Oxydrol, - British Dragon 50mg x 100 tablets
Oxymetholone 50mg x 100 tablets
Primobolan Depot 1 ampule x 1ml, 100mg in 1 ml
Primoteston Depot 1 ampule x 1ml, 250mg in 1 ml
Propionator 200 1 vial x 10ml, 200mg per ml
Restandol 60 60 capsules x 40mg
Sostenon 250 1 ampule x 1ml, 250mg/ml
SustaJect 250 1 vial x 10ml, 250mg/ml
Sustanon 250 1 ampule x 1ml, 250mg/ml
Sustanon 250 (4 Testosterones) 250mg/1ml 1 ampule x 1ml, 250mg/ml
Sustanon 250 1 ampule x 1ml, 250mg/ml
Sustor 250 (4 Testosterones) 1 vial x 10ml, 250mg per 1 ml
Testabol Depot / testosterone cypionate 1 vial x 10ml, 200mg per 1 ml
Testabol Depot (Testosterone Cypionate) 1 vial x 10ml, 200mg per 1 ml
Testabol Enanthate BD (1 vial) 1 vial x 10ml, 250mg/1ml
Testabol Enanthate BD (10 vials) 10 vial x 10ml, 250mg/1ml
Testabol Propionate 100 (1 vial) 1 vial x 10ml, 100mg/1ml
Testabol Propionate 100 (10 vial) 10 vials x 10ml, 100mg/1ml
Testex Prolongatum 250mg 1 ampule x 2ml, 250mg/2ml
Testoject (Aquaviron Testosterone Suspension) 10 ml bottle (250 mg/ml)
Testole Depot 10 ml bottle (250 mg/ml)
Testolic 100 10 x 2ml ampules, 100mg/ml
Testoprop (Testosterone Propionate) 10x1ml Amps. 10 x 1ml ampules, 50mg/ml
Testosterone (Testosterone Enanthate + 324 mg Benzyl Benzoate + 440mg Castor Oil/ml) 20 x 1ml ampules, 250mg/ml
TESTOSTERONE COMPOUND (Sustanon) 1 vial x 10ml, 250mg/ml
Testosterone cypionate 1 vial x 10ml (200mg/ml)
Testosterone Enanthate 250 10 ampules x 1ml, 250mg/ml
Testosterone Enanthate 250mg/1ml Norma 1 ampule x 1ml, 250mg/ml
Testosterone Propionate 5 ampules x 1ml (contains 50mg in 1 ml)
Testosterone suspension 12 ampules x 1ml (200mg/ml)
Testoviron Depot 20 ampules x 1ml (250mg/ml)
TESTOVIS / TESTOSTERONE PROPIONATE 2 ampules x 2ml (100mg/2ml)
Trenabol 75 1 vial x 10ml, 75mg/1ml
Tri-Trenabol 150 1 vial x 10ml, 50mg/1ml
Turanabol 10mg 200 tablets x 10mg
Vironate 2 vials x 5ml Vial, 200mg/1ml
Virormone 2ml 10 ampules x 2ml, contains 100mg per ampule (50mg/1ml)




Cutting Steroids:
Aldactazide 25mg x 20 tablets
Anadiol Depot 1 vial x 10ml, 75mg/ml
Boldabol 200 1 vial x 10ml, 200mg/ml
Boldenol 100 1 vial x 10ml, 100mg/ml
Bonavar 50 tablets x 2.5mg
BU - Equipoise 1 x 3 ml (3.5 ml) Sachet, 200 mg/ml
Cetabon 200 tablets x 2mg
Danabolan 2 ampules x 1.5ml, 76mg/1.5ml
Drive RWR 1 vial x 10ml (25mg/ml)
Equilon 1 vial x 6ml, 100mg per 1ml
Equipoise 1 vial x 50ml (50mg/1ml)
Ilium Stanabolic 1 vial x 20ml (50mg/ml)
Lasix 12 tablets x 40mg
Mastabol 100 1 vial x 10ml (100mg/ml)
Mastabol Depot 200 1 vial x 10ml (200mg/ml)
Masteron 100 1 vial x 20ml, 100mg/1ml
Parabolan 25mg x 20 tablets
Primobol 50 50mg x 30 tablets
Primobol-100 1 vial x 10ml, 100mg per ml
Primobolan Depot (Methenolone) 1ml 1 ampule x 1ml (100mg/ml)
Primobolan Depot (Methenolone Enanthate) 25ml 25 ampules x 1ml (100mg/ml)
Primoject 10ml vial contains 1000mg 1 vial x 10ml, 100mg/1ml
Protabol (methandriol dipropionate) 75mg/ml, 10ml vial 1 vial x 10ml (75mg/ml)
Stanabol 10mg (Stanozolol) BD, 100 tabs 100 tablets x 10mg
Stanabol 10mg (Stanozolol) BD, 500 tabs 500 tablets x 10mg
Stanabol 50injectable (Stanozolol) BD 1 vial x 10ml (50mg/ml)
Stanabol 50mg (Stanozolol) BD 50mg x 100 tablets
Stanabol 50mg (Stanozolol) BD 500 tabs 50mg x 500 tablets
Stanabol 50mg (Stanozolol) C&K 50mg x 100 tablets
Stanabol 5mg (Stanozolol) 5mg x 1000 tablets
Stanazol (Stanozolol) 50mg/ml, 20ml vial 1 vial x 20ml, 50mg/ml
Stanoject (Stanozolol) 10 ml, 50mg/ml 1 vial x 10ml, 50mg/ml
STANOL (stanozolol) 5 mg 200tabs 200 tablets x 5mg
Stanol 50mg/1ml (stanozolol) 1 ampules x 1ml, 50mg/1ml
Stanol 50mg/1ml (stanozolol) 100 amps 100 ampules x 1ml, 50mg/1ml
STANOZOLOL (Winstrol) 1ml x 50mg/ml 1 vial x 1ml, 50mg/ml
Stanozolol 10mg 100Tabs 10mg x 100 tablets
STANOZOLOL 50mg/ml (ILIUM) 1 vial x 20ml, 50mg/ml
Testolic (Testosterone Propionate) 100mg/ml, 2ml amps 10 ampules x 2ml, 100mg/ml
TESTOPIN-100 3 vials x 2ml (200 mg/2ml)
Trenabol 200 1 vial x 10ml, 200mg/1ml
Trenabol 75 1 vial x 10ml, 75mg/1ml
Trenabol depot 100 1 vial x 10ml, 100mg/1ml
Trenbola 100 1 vial x 10ml, 100mg/1ml
Trenbolone Acetate 25 mg 25mg x 20tablets
Trenbolone Depot 1 vial x 10ml, 200mg/ml
Tri-Trenbola 150 1 vial x 10ml, 150mg/1ml
Turanabol 200 BD 200 tablets x 10mg
Virormone 2ml 10 ampules x 1ml, 100mg per ml
Voltaren 75 Diclofenac sodium 75mg x 100 tablets
Winstrol (Stanozolol) / 20mg 50tabs 20mg x 50 tablets
Winstrol Depot (stanozolol) 50mg 3 ampules x 1ml, 50mg per ml




Men\'s Health:
Apcalis 20mg 50 Sachets x 5gm
Caverject 1 kit
Cialis 20mg 4 tablets x 20mg
Cialis 25mg 50 tablets x 25mg
Kamagra Gold 4 tablets x 100mg
Kamagra Jelly 10 Jelly x 100mg
Propecia 1mg 28 tablets x 1mg
Viagra 30 tablets x 100mg
Viagra 100mg 4 tablets x 100mg




:
Caverject 20mcg, Syringes 1 Syring
Caverject 1 kit




Hormones:
Choriomon 5000 IU 3 vials x 5000 IU
Chorionic Gonadotropin 10 x 2000 IU 10 vials x 2000 IU
Chorionic Gonadotropin 10 x 5000 IU 10 vials x 5000 IU
EPIAO 10000IU/1ml 10 vials x 10000 IU
EPIAO 2000IU/1ml 10 vials x 2000 IU
Humatrope 4 Vials x 15 IU/5mg
Humulin 5 Vials x 100 IU/3ml
IGF1 Long R3 100mcg per Vial 100mcg per Vial x 10 Vials per box
Jintropin 10IU (100IU/box) 10IU x 10 bottles
Jintropin 4IU (40IU/box) 4IU x 10 bottles
Jintropin AQ 30iu (150iu/kit) 30IU x 5 bottles
Jintropin AQ 30iu (300iu/kit) 30IU x 10 bottles
Norditropin (HGH) 4iu (1.3mg) + Solvent 10 vials x 4IU/1.3mg
Pregnyl 5000 IU 1 x 5000 IU + 1amp. solvent
Pregnyl 15000 IU 3 x 5000 IU + 1amp. solvent
Riptropin 10iu vial - (100ui kit) 10 vials x 10 IU
Somatropin 8IU, (80IU per kit), 10 vials 10 vials x 8 IU + 10 vials Sodium Chloride Injection Water
SymbioTropin Pro HGH 40 tabs 40 tablets




Anti Estrogens:
Anastrozole 1mg 50 tablets x 1mg
Anastrozole / Altraz 1mg 28 tablets x 1mg
Arimidex / Anastrozole 1mg 28 tablets x 1mg
Aromasin 20mg / Exemestane Tablets 50 tablets x 20mg
Aromasin 25 mg / Pfizer 30 tablets x 25mg
Aromasin 25 mg / Pharmacy & UpJohn 30 tablets x 25mg
Capoten / Captopril 60 tabs 25mg 60 tablets x 25mg
Cialis, 20mg, Tadalafil 4 tablets x 20mg
Cialis, 20mg, Tadalafil, (bottle type) 30 tablets x 20mg
Cialis, 25mg C&K 50 tablets x 25mg
Clenbuterol 40mcg 100 Tabs 100 tablets x 40mcg
Clenbuterol / Hubei Huangshi 50 tablets x 40mcg
Clenbuterol / Hydrochloride 20mcg 200 tablets x 20mcg
Clenbuterol / Hydrochloride 0,02 mg 200 tablets x 20mcg
Clomid (Clomiphene Citrate) 50mg 30 tablets x 50mg
Clomid 50mg Clomiphene citrate 100 tablets x 50mg
Clomid 50mg, Aventis 30 tablets x 50mg
Clomid 50mg, Brunno Farmaceutici 50 tablets x 50mg
Clomifen 25 mg 20 capsules x 25mg
Clomiphene (Clomiphene Citrate) 50mg 15 tablets x 50mg
Clomiphene 50mg Clomifene citrate 50 tablets x 50mg
Clomiphene Citrate 12 Tabs/50mg 12 tablets x 50mg
Clomiphene citrate 50mg 24 tablets x 50mg
Clostilbegyt (Clomiphene) 50mg 10 tablets x 50mg
Eltroxin (T4) (Thyroxin Sodium) 100mcg 1000tabs 1000 tablets x 100mcg
Euthyrox 100 (Levothyroxine Sodium/T4)100mg 100 tablets x 100mg
Euthyrox 100 (Levothyroxine Sodium/T4)50mg 100 tablets x 50mg
GP Letrozole (20 tabs 2.5 mg/tab) 20 tablets x 2.5mg
Legalon 70 (70mg Thistle Milk Fruit Extract) 100 capsules x 70mg
Liv-52 (100 Tabs per bottle) 100 tablets
Mesterolone BD (Proviron) 50 tablets x 50mg
Nolvadex (Tamoxifene) 10mg 30 tablets x 10mg
Nolvadex 10mg 30 tablets x 10mg
Nolvadex, 20mg, AstraZeneca 300 tablets x 20mg
Nolvadex, 40mg, AstraZeneca 100 tablets x 40mg
Nolvadex, 50mg 100 tablets x 50mg
Omifin 50 mg 30 tablets x 50mg
Ovinum (Clomiphene Citrate) 50mg 10 tablets x 50mg
Proviron (Mesterolone) 25mg 20 tablets x 25mg
Proviron (Mesterolone) 50mg 20 tablets x 50mg
Proviron 25mg Mesterolone 20 tablets x 25mg
Provironum (Mesterolone) 25mg / 150 Tabs 150 tablets x 25mg
Provironum 25 mg / (Mesterolone) 30 tablets x 25mg
Spiropent (Clenbuterol) 100 Tabs/20mcg (Clenbuteroli Hydrochloridum) 100 tablets x 20mcg
Tamoxifen (Tamoxifeni Dihydrogenocitras) 10mg/100 Tabs 100 tablets x 10mg
Teslac (Testolactone) 50mg / 100 tabs 100 tablets x 50mg
Tiratricol (T3) 50 x 1mg tablets 50 tablets x 1mg
Xenical (Orlistat) 84 x 120mg capsules 84 capsules x 120mg




Anti Depressants:
Rivotril (CLONAZEPAM) 2 mg 100 tablets x 2mg
Rivotril (Clonazepam) 2mg 60tabs 60 tablets x 2mg
Rohypnol (Flunitrazepam) 1mg 30 tablets x 1mg
Valium (Diazepam) 10mg 50tabs 50 tablets x 10mg
Valium (DIAZEPAM) 5mg 60tabs 60 tablets x 5mg




Head Ache:
Maxalt (Rizatripan) 10 mg 3 tablets x 10mg
Relpax 40mg 2 tablets x 40mg
Zomigon (Zolmitriptane) 2.5mg 3 tablets x 2.5mg




Herpes:
Famvir (Famciclovir) 125 mg 10 tablets x 125mg
Viranet / Valtrex (Valacyclovir) 500mg 10 tablets x 500mg
Zovirax, 5%, 15 gm Tube (Acyclovir) 1 tube




Muscle Relaxers:
Baclofen 25mg 50 tablets x 25mg
Muscoril Caps 20 x 4 mg 20 capsules x 4mg
Norgesic generic (Nuberol) (Orphenadrine) 100 tablets




Pain Releaf:
Advil (Ibuprofen) 200mg 325 tablets x 200mg
Celebrex 200mg 120caps 120 capsules x 200mg
Celebrex 200mg 120caps 20 capsules x 200mg
Mesulid (Nimesulide) 100mg 30 tablets x 100mg
Movatec (Meloxicam) 15mg 60 tablets x 15mg
Naprosyn 500mg 20 tablets x 500mg
Oruvail (Ketoprofen) 200mg 14 tablets x 200mg
Vioxx 25mg 90 tablets x 25mg




Quit Smoking:
Zyban (bupropion) 150 mg 60 tablets x 150mg




Weight Loss:
Cytomel / T3 (liothyronine sodium) 50mcg / 100 Tabs 100 tablets x 50mcg
Cytomel / T3 / Cynomel / Liothyronine Sodium 30 tablets x 0.25mg
Cytomel / T4 50 mg (levothyroxine sodium) 200 tablets x 50mg
DNP (2,4-Dinitrophenol) 100 mg Capsules 100 capsules x 100mg
Helios - Clenbuterol & Yohimbine HCL blend 1 vial x 50 ml
Phentermine (blue/clear) 30mg. 100 Caps 100 capsules x 30 mg
Reductil 15mg Sibutramine Hydrochloride 28 tablets x 15mg
T3 Cytomel (Liothyronine Sodium) 100mcg / 100 Tabs 100 tablets x 100mcg
Thiomucase cream (mucopolisacaridasa) 100 mg/Tube 100 tablets x 100mg
TRIACANA 0.35 mcg (3,5,3-triiodothyroacetic acid - Tiratricol) 100 tablets x 0.35 mcg
Xenical 120mg 168 tablets x 120mg




Genital Warts:
Aldara cream 5% (Imiquimod) 12 Sachets
Wartek (Podophyllotoxin) cream 5 gr x 0,15% 1 tube




Anti-hair loss:
Harifin 5 (Finasteride) 5mg 30 tablets x 5mg
Propecia (Finasteride) 1mg 30 tablets x 1mg
Proscar (Finasteride) 5mg / 15 Tabs 15 tablets x 5mg




Stimulants:
Efedrina Level 25mg (Efedrina Clorhidrato) 50 tablets x 25mg
Nucofed (Ephedrine) 60 capsules x 25mg




Rhgh-hgh-guide-samotropin

Rhgh hgh guide samotropin

rHGH Guide



According to studies in the New England Journal of Medicine GH use will:
Shed Bodyfat, Increase Muscle Tone; Boost your Energy, Strength, and Endurance
Reduce Wrinkles and Create Tighter, Smoother Skin; Help you Sleep Better, Improve Sex Drive and Performance, Improve Immune and Heart Function, Bone Density, Healing Time and Cholesterol, Improve Brain Function, Memory and Mental Focus

Wow! Sure sounds like a wonder drug to me! Yeah right, anyway here is some real world information for bodybuilders. Somatropin (rHGH) is produced by the pituitary gland and is responsible in adolescence for growth of tissues, protein deposition, and the breakdown of sub-q fat stores. As we age, growth hormone levels decrease but still remain active in the body, releasing in cycles during the day. Synthetic growth hormone used exogenously by bodybuilders is a 191 chain sequence of amino acids that replicates the bodies natural production of growth hormone.

Growth hormone has been in use by bodybuilders since the early 1980Тs, though at this time, HGH was being extracted from the pituitary glands of cadavers and had enormous side effects, most prominently Creutzfeldt Jacob disease. This is a rare and fatal brain disease, it need not be discussed here since it is not possible in synthetic forms of rHGH, but if you want more info just run a search in google. rHGH stimulates growth in most body tissues which is due to an increase in cell number rather than cell size. This includes muscle tissue as well as internal organs, hence the dreaded GH gut.

Use of growth hormone by bodybuilders will cause increased muscle size, localized and overall bodyfat loss, increased protein synthesis, increased glucose output by the liver, increased insulin resistance and lowered thyroid output. Stored fats will be used as a primary fuel source, thus the body fat loss.

So is rHGH the wonder drug everyone lusts after? It certainly is beneficial but not for everyone. You must be willing to take risks to achieve maximum benefits from its use, as well as substantial financial investment. Do it right the first time or donТt do it at all! You will achieve faster and greater growth from cycles of steroids than with GH, though once you reach a plateau, not many products work better.

Ok, so now you have decided that this is the drug for you and you are ready to try it, so what next? Well here are some general guidelines to follow for maximal results from GH use:

Daily injections are a must to maintain stable blood levels as GH has a very short life span in the body. It will peak almost immediately after injection and will clear the body with a half-life of only 20-30 minutes. It is best injected first thing in the morning upon rising to raise levels that are very low from sleeping, and immediately after training. I do not recommend injecting before bed as many bodybuilders do, since that is the time of day that your body will release naturally high levels of growth hormone, and exogenous use will only block that release. If you take it in the morning when levels are low, after training when levels are depleted and then let your body release while sleeping, you are getting one extra release for free! GH is best taken long term, short cycles do not maximize the benefits of muscle cell increase, only fat loss. Here is how I take my GH for maximum benefits:

6iu ed injected sub-q, preferably in the stomach
3iu injected upon rising, 3iu injected immediately post-workout
10iu insulin taken 30 minutes after GH injection
25mcg cytomel ed
use of androgens such as testosterone

The timing of GH and insulin injections is critical. If insulin is injected before the GH, your pancreas will stop release of insulin monitoring due to the exogenous source. GH when injected will mobilize stored glycogen release which will turn into glucose for energy. This will cause a rapid rise in blood sugar levels that will not shut down or stop rising due to the feedback loop being momentarily cut off. You will go hyperglycemic and end up in the hospital. You must first inject your GH, then the insulin; this will cause a rise in glucose release by the GH and will be controlled and shuttled into muscle tissue for repair by the later injection of insulin.
Use of cytomel or some type of T3 hormone is critical since GH use will severely lower thyroid levels. Small exogenous sources are necessary to maintain normal levels and 25 mcg ed is sufficient. This will also aid in body fat loss by maintaining proper thyroid functioning.
Use of androgens is also necessary due to the promotion of anabolism by increasing muscle size that benefits the new cell number increase by the GH. Remember GH will not directly cause muscle cell size increase, just the number of cells, therefore, androgens are necessary to increase size. Testosterone or trenbolone are both highly androgenic and perfect for out stack.

One myth that needs to be cleared up: high doses of GH use and the 5 on 2 off program. First, if you find that you are not achieving results off of 4-6iu ed, than something else is the problem, not your dose. The use of high doses if primarily cause by heat damage to the protein chain causing denatured proteins. This will decrease the effect and you must use higher doses to achieve the same effect. Other reasons for high dose use are; fake gh, not using insulin, cytomel or test, poor diet, improper timing schedule and the 5 on 2 off. This program was recommended by dealers as a way to move product by offering a lower cost cycle. No doctor in the world would recommend this protocol, Peak blood concentrations are reached in 2-6 hours after injection, and therefore, multiple daily injections are necessary to achieve stable release schedule and results. If you take your last injection Friday afternoon, and then not again till Monday morning, then you have negated all effects offered by the 6 hour concentration. Yes, you will achieve results using a 5 on 2 off program, but not as well as if you inject ed. ItТs your money; I can only tell you how to optimize use.

Side effects of GH use include; carpal tunnel syndrome, tingling in the extremities, numbness in the hands and feet, increased organ growth, decreased insulin reception, acromegaly but only in extreme dose use, and decreased thyroid output causing fat accumulation. If you find that you are experiencing any of the above side effects, lower your dose immediately. This is especially important with carpal tunnel. If you feel like your wrists are hurting then lower the dose until pain subsides. You do not want to have that surgery, trust me.

GH is a fantastic product, beneficial for many reasons. Most people will experience thinning of the skin, increased vascularity, fat loss, permanent increases in muscle size due to the cell number increase, and overall feelings of wellness. You will probably need less sleep and feel supercharged all day long. I highly recommend GH use, but only when you have the money to do it right. 4-6 month cycles are optimal, year round if you are over age 35. If you have anything of benefit to add to this thread, feel free to contribute or PM me.

This was posted in the "Very Basix Question on T3/ GH" thread by Mr. Vic. All thanks go to him. But I was wondering if you had any input, especially the final conclusion at the very end of the artice: "If youТve been using GH without T4, youТve been wasting half your money Ц and if youТve been using it with T3, youТve been wasting your time. Start using T4 with your GH, and youТll finally be getting the full results from your investment."


Thyroid Hormone + Growth Hormone
(IF you arenТt using T4 with your GH, youТre not doing it right)
By Anthony Roberts with James Daemon, PhD.



Quite some time ago, I wrote a book on Anabolics, and since then, IТve received quite a bit of feedback on it. Some of the information contained in the book is based on the 50-60 profiles I completed for Steroid.comТs main page. As a result, I get feedback on certain portions of the book from people who have read them online.

When someone takes the time to send an e-mail to Steroid.com or AnabolicBooks LLC, theyТre screened, and eventually some of them make their way to my e-mail account. AnabolicBooks LLC is publisher- a little known fact is that my book is actually wasnТt edited by me, nor do I own the rights to any of it. When they forward an e-mail to me, I typically consider it very carefully, and reply to the original sender. If amendments or additions are useful for anything IТve previously written (readers frequently send me recently published studies), I typically reply and thank the person for their help.

This time, something odd happened. I was forwarded an e-mail from AnabolicBooks, and the reader seemed to know what he was talking about, but (I thought) mistaken about interactions between Growth Hormone and Thyroid medication. I took a look at the e-mail, and knew that I could quickly find a study that I had saved previously, to send to the reader, to verify that the claims in my work on GH were sound.

In this particular case- James Daemon, PhD- was the reader, and was correct in his assessment of the interaction between thyroid hormone and Growth Hormone. And, in direct contradiction, so was I. Thyroid medication decreases the anabolic effect of Growth Hormone. And it increases it.
Huh?

ThereТs some leaps here, because research in some of the necessary areas is sketchy (or not done yet), but if you read the entirety of this article, youТll learn how to get a significantly more gains from Growth Hormone, for pennies a day, by the addition of a readily available (and cheap) addition to it. And yeah, itТs a drug you can get anywhere on the Сnet, very easily. And no, itТs not a steroid.
In fact, IТll go so far as to say youТre throwing away a substantial portion of your gains from growth hormone if you are not using this drug with it.

OkЕIТll explain things a bit further. First, a brief explanation of Thyroid Hormone as well as Growth Hormone may be necessary.

Your thyroid gland secretes two hormones that are going to be of primary importance in understanding Thyroid/ GH interaction. The first is thyroxine (T4) and the second is triiodothyronine (T3). T3 is frequently considered the physiologically active hormone, and consequently the one on which most athletes and bodybuilders focus their energies on. T4, on the other hand, is converted in peripheral tissue into T3 by the enzymes in the deiodinase group, of which there are three types- the three iodothyronine deiodinase either catalyze the initiation (D1, D2) or termination (D3) of thyroid hormone effects. The majority of the body's T3 (about 80%) comes from this conversion via the first two types of deiodinase, while conversion to an inactive state is accomplished by the third type.

ItТs important to note that not all of the bodyТs T4 is converted to T3, however- some remains unconverted. The secretion of T4 is under the control of Thyroid Stimulating Hormone (TSH) which is produced by the pituitary gland. TSH secretion is in turn controlled through release of Thyrotropin Releasing Hormone which is produced in your hypothalamus. So, when T3 levels go up, TSH secretion is suppressed, due to the bodyТs self regulatory system known as the Уnegative feedback loopФ . This is also the mechanism whereby exogenous thyroid hormone suppresses natural thyroid hormone production. However, it should be noted that thyroid stimulating hormone (like all other hormones) can not work in a vacuum. TSH also requires the presence of Insulin or Insulin-like Growth Factor to stimulate thyroid function (1) When thyroid hormone is present without either insulin or IGF-1, it has no physiological effect (ibid).

Most people think that T3 is just a physiologically active hormone that regulates bodyfat setpoint and has some minor anabolic effects, but in actuality, in some cases of delayed growth in children, T3 is actually too low, while GH levels are normal, and this has a growth limiting effect on several tissues (2) This could be due to T3Тs ability to stimulate the proliferation of IGF-1 mRNA in many tissues (which would, of course, be anabolic), or it could be due to the synergistic effect T3 has on GH, specifically on regulation of the growth hormone gene. Although it is largely overlooked in the world of performance enhancement, regulation of the growth hormone response is predominantly determined by positive control of growth hormone gene transcription which is proportional to the concentration of thyroid hormone-receptor complexes, which are influenced by T3 levels. (3)

At this point, just to give you a better understanding of whatТs going on, I think itТs prudent to also give a brief explanation of Growth Hormone ( GH) as well.

Your bodyТs GH is regulated by many internal factors, such as hormones and enzymes. hormones. A change in the level of your bodyТs GH output begins in the hypothalamus with somatostatin (SS) and growth hormone-releasing hormone (GHRH). Somatostatin exerts its effect at the pituitary to decrease GH output, while GHRH acts at the pituitary to increase GH output. Together these hormones regulate the level of GH you have in your body. In many cases, GH deficiency presents with a low level of T3, and normal T4(
4). This is of course because conversion of T4-T3 is partially dependant on GH (and to some degree GH stimulated IGF-1), and itТs ability to stimulate that conversion process of T4 into T3.

Interestingly, the hypothalamus isnТt the only place where SS is contained; the thyroid gland also contains Somatostatin-producing cells. This is of interest to us, because in the case of the thyroid, itТs been noted that certain hormones which were previously thought only to govern GH secretion can also influence thyroid hormone output as well. SS can directly act to inhibit TSH secretion or it may act on the hypothalamus to inhibit TRH secretion. So when you add GH into your body from an outside source, you are triggering the body into releasing SS, because your body no longer needs to produce its own supply of GHЕand unfortunately, the release of SS can also inhibit TSH, and therefore limit the amount of T4 your body produces.
But thatТs not the only interaction we see between the thyroid and Growth Hormone.
As we learned in high-school Biology class, the body likes to maintain homeostasis, or УnormalФ operating conditions. This is the bodyТs version of the status quo, and it fights like hell to maintain the comfort of the status quo (much like moderators on most steroid discussion boards). What we see with thyroid/ GH interplay is that physiological levels of circulating thyroid hormones are necessary to maintain normal pituitary GH secretion, due to their directly stimulatory actions. However, when serum concentrations of thyroid hormone increase above the normal range we see an increase in hypothalamic somatostatin action, which suppresses pituitary GH secretion and overrides any stimulatory effects that the thyroid hormone may have had on GH. The suppression of GH secretion by thyroid hormones is probably mediated at the hypothalamic level by a decrease in GHRH release(5).
In addition, as IGF-I production is increased in the hypothalamus after T3 administration and T3 may participate in IGF-1 mediated negative feedback of GH by triggering either increased somatostatin tone and/or decreased GHRH production (6). IGF, interestingly, has the ability to mediate some of T3Тs effects independent of GH, but not to the same degree GH can (7.) In fact, IGF-I production is increased in the hypothalamus after T3, administration it may plausibly participate in negative feedback by triggering either increased somatostatin tone and/or decreased GHRH production. So we know that GH lowers T4 (more about this in a sec), but an increase in T3 upregulates GH receptors (8) as well as IGF-1 receptors (9,10).

As can be previously stated, and due to the ability of GH to convert inactive T4 into active T3, GH administration in healthy athletes shows us an entirely predicatble increase in mean free T3 (fT3), and a decrease in mean free T4 (fT4) levels.(11)


Interaction between GH, IGF-I, T3, and GC. GH stimulates hepatic IGF-I secretion and local production of growth plate IGF-I, and exerts direct actions in the growth plate. Circulating T3 is derived from the thyroid gland and by enzymatic deiodination of T4 in liver and kidne.. The regulatory 5'-DI and 11яHSD type 2 enzymes may also be expressed in chondrocytes to control local supplies of intracellular T3 and GC. Receptors for each hormone (GHR, IGF-IR, TR, GR) are expressed in growth plate chondrocytes.


So, with the use of GH, what we see is an increased conversion of T4-T3, and possible inhibition of Thyroid Releasing Hormone by Somatostatin, and therefore even though T3 levels may rise, there is no increase in T4 (logically, we see a decrease). Now, as weТve seen, GH is HIGHLY synergistic with T3 in the body, and as a mater of fact, if youТve been paying any attention up until this point, youТll note that the limiting factor on GHТs ability to exert many of itТs effects, is mediated by the amount of T3 in the body.

As noted before, T3 enhances many effects of GH by several mechanisms, including (but not limited to): increasing IGF-1 levels, IGF-1 mRNA levels, and finally by actually mediating the control of the growth hormone gene transcription process as seen below:


Comparison of the kinetics of L-T3-receptor binding abundance to changes in the rate of transcription of the GH gene.(3)

As you can see, T3 levels are directly correlative to GH gene transcription. The scientists who conducted the study which provided the graph above concluded that the amount of T3 present is a regulatory factor on how much GH gene transcription actually occurs. And gene transcription is what actually gives us the effects from GH. This last fact really seems to shed some light on why we need T3 levels to be supraphysiological if weТre going to be using supraphysiological levels of GH, right? Otherwise, the GH weТre using is going to be limited by the amount of T3 our body produces. However, since weТre taking GH, and it is converting more T4 into T3, T4 levels are lowered substantially, and this is the problem with GH. and may actually be THE limiting factor on GHЕif we assume that at least some of GHТs effects are enhanced by thyroid hormone, and specifically T3, then what we are looking at is the GH that has been injected is being limited by a lack of T3. But that doesnТt make sense, because if we use T3 + GH, we get a decrease in the anabolic effect of GH.

This is where Mr. Daemon, who had contacted me via an e-mail to my publisher, about Thyroid + GH interaction, was able to shed some light on things. You see, I knew that it couldnТt just be the actual presence of enough T3 along with the GH that was limiting GHТs anabolic effect, because, simply adding T3 to a GH cycle will reduce the anabolic effect of the GH (12.).

Originally, he had said to me that T3 was synergistic with GH, wheras I said that T3 actually reduced the anabolic effects of GH- now I realize we were both correct. Logically this presents a bit of a problem, which I believe can be solved. This came from reading several studies provided to me by Dr.Daemon. the trend I was seeing was that even when Growth Hormone therapy was used, T3 levels needed to be elevated in order to treat several conditions caused by a lack of natural growth hormone. And even if the patient was on GH, T3 levels still needed to be elevated. And what I noticed was that those levels were elevated successfully by using supplemental T4 but not T3.

HereТs why I think this is:

Additional T3 is not all thatТs needed here. WhatТs needed is the actual conversion process of T4-T3, and the deiodinase presence and activity that it involves. This is because Local 5'-deiodination of l-thyroxine (T4) to active the thyroid hormone 3,3',5-tri-iodothyronine (T3) is catalyzed by the two 5'-deiodinase enzymes (D1 and D2). These enzymes not only УcreateФ T3 out of T4, but actually regulates various T(3)-dependent functions in many tissues including the anterior pituitary and liver. So when there is an excess of T3 in the body, but normal levels of T4, the bodyТs thyroid axis sends a negative feedback signal., and produces less (D1 and D2) deiodinase, but more of the D3 type, which signals the cessation of the T4-T3 conversion process, and is inhibitory of many of the synergistic effects that T3 has! Remember, Type 3 iodothyronine deiodinase (D3) is the physiologic INACTIVATOR of thyroid hormones and their effects (13) and is well known to have independent interaction with growth factors (which is what GH and IGF-1 are).(14) This is because with adequate T4 and excess T3, (D1 and D2) deiodinase is no longer needed for conversion of T4 into T3, but levels of D3 deiodinase will be elevated. When there is less of the first two types of deidinase, it would seem that the T3 which has been converted to T4 can not exert itТs protein sparing (anabolic effects), as those first two types are responsible for mediation of many of the effects T3 has on the body. This seems to be one of the ways deiodinase contributes to anabolism in the presence of other hormones.

All of this would explain why anecdotally we see bodybuilders who use T3 lose a lot of muscle if they arenТt using anabolics along with it- theyТre not utilizing the enzyme that would regulate some of T3Тs ability to stimulate protein synthesis, while they are simultaneously signaling the body to produce an inhibitory enzyme (D3). And remember, for decades bodybuilders who were dieting for a contest have been convinced that you lose less muscle with T4 use, but that itТs less effective for losing fat when compared with T3? Well, as weТve seen, without something ( GH in this case) to aid in the conversion process, it would clearly be less effective! Since the deiodinase enzyme is also located in the liver, and we see decreased hepatic nitrogen clearance with GH + T3, it would seem that the D3 enzyme is exerting itТs inhibitory effects, but in the absence of the effects of the first two deiodinase enzymes, it remains unchecked and therefore not only limits the GHТs nitrogen retention capability.

In other words, if we have enough to GH in our body aid in supraphysiological conversion of T4 into T3, but we already have the too much (exogenous) T3, the GH is not going to be converting any excess T4 into T3 after a certain point- which would be a limiting factor in GHТs anabolic effects, when coupled with the act that weТve allowed the D3 enzyme to inhibit the T3/ GH synergy that is necessary.

As further evidence, when we look at certain types of cellular growth (the cartilage cell in this case) we see that GH induced rises in IGF-I stimulates proliferation, whereas T3 is responsible for hypertrophic differentiation. So it would seem that in some tissues, IGF-1 stimulates the synthesis of new cells, while T3 makes them larger. In this particular case, The fact that T4 and (D1) deiodinase is am
active component in this system is noted by the authors. They clearly state (paraphrasing) that: УT4 is is converted to T3 by deiodinase (5'-DI type 1) in peripheral tissuesЕ[furthermore] GH stimulates
conversion of T4 to T3 , suggesting that some effects of GH
may involve this pathway.Ф The thing I want you to notice is that the authors of this paper state that the that the conversion PATHWAY is probably involved, and not the simple presence of T3. (15 )

Also, that same study notes that T3 has the ability to stimulates IGF-I and expression in tissues that whereas GH has no such effect (ibid).


So what are we doing when we add T3 to GH? WeТre effectively shutting down the conversion pathway that is responsible for some of GHТs effects! And what would we be doing if we added in T4 instead of T3? You got it- weТd be enhancing the pathway by allowing the GH weТre using to have more T4 to convert to T3, thus giving us more of an effect from the GH weТre taking. Adding T4 into our GH cycles will actually allow more of the GH to be used effectively!


Remember, the thing that catalyzes the conversion process is the deiodinase enzyme. This is also why using low amounts of T3 would seem (again, anecdotally in bodybuilders) to be able to slightly increase protein synthesis and have an anabolic effect Ц they arenТt using enough to tell the body to stop or slow down production of the deiodinase enzyme, and hence .Although this analogy isnТt perfect, think of GH as a supercharger you have attached to your carЕif you donТt provide enough fuel for it to burn at itТs increased output level, you arenТt going to derive the full effects. Thyroid status also may influence IGF-I expression in tissues other than the liver.So what we have here is a problem. When we take GH, it lowers T3 levelsЕbut we need T3 to keep our GH receptor levels optimally upregulated. In addition, itТs suspected that many of GHТs anabolic effects are engendered as a result of production of IGF-1, so keeping our IGF receptors upregulated by maintaining adequate levels of T3 seems prudent. But as weТve just seen, supplementing T3 with our GH will abolish Growth HormoneТs functional hepatic nitrogen clearance, possibly through the effect of reducing the bioavailability of insulin-like growth
factor-I (12.)

So we want elevated T3 levels when we take GH, or we wonТt be getting ANYWHERE NEAR the full anabolic effect of our injectable GH without enough T3. And now we know that not only do we need the additional T3, but we actually want the CONVERSION process of T4 into T3 to take place, because itТs the presence of those mediator enzymes that will allow the T3 to be synergistic with GH, instead of being inhibitory as is seen when T3 is simply added to a GH cycle. And remember, we donТt only want T3 levels high, but we want types 1 and 2 deiodinase to get us there- and when we take supplemental T3, that just doesnТt happenЕall that happens is the type 3 deiodinase enzyme shows up and negates the beneficial effects of the T3 when we combine it with GH.


And thatТs where myself and Dr. Daemon ended up, after a week of e-mails, researching studies, and gathering clues.

If youТve been using GH without T4, youТve been wasting half your money Ц and if youТve been using it with T3, youТve been wasting your time. Start using T4 with your GH, and youТll finally be getting the full results from your investment.


anabolex.com
























Home | F.A.Q. | Terms & Conditions | Contact us
 
© 2005-2018 bulkpharmausa.com