This section refers to the oral Primobolan preparation. The steroid contains the primobolan acetate. Primobolan Oral is very similar in action to the injectable Primobolan Depot (methenolone enanthate), but obviously here the anabolic steroid is designed for oral administration. At one time Schering was in fact also manufacturing an injectable methenolone acetate (Primobolan acetate, out of manufacture since 1993), which proved to be very useful for pre-contest cutting purposes. The steroid is now gravely missed, as it was once a favorite among European competitors. Although we still have Primobolan acetate in oral form, it is a close, but not equal substitute (injection is a much more efficient form of delivery for the drug).
Primobolan acetate regardless of the ester is a very mild anabolic steroid. The androgenic activity of drug is considerably low, as are its anabolic properties. One should not expect to achieve great gains in muscle mass with this drug. Instead, Primobolan depot is utilized when the athlete has a specific need for a mild anabolic agent, most notably in cutting phases of training. It is also a drug of choice when side effects are a concern. A welcome factor is that steroid is not c17 alpha alkylated as most oral steroid are. Due to the absence of such an alteration, Primobolan depot is one of the few commercially produced oral steroids that is not notably stressful to the liver. While liver enzymes values have been affected by Primobolan depot in some rare instances, actual damage due to use of Primobolan is not a documented problem. Unfortunately the 1 alkylation and 17-beta esterification of the anabolic steroid do not protect the compound very well during first pass however, so much of your initial dose will not make circulation. This is obviously why we need such high daily dose with the oral version of the drug.
Primobolan depot is indispensable to the competitor
Primobolan will also not aromatize, so estrogen related side effects are of no concern. This is very useful when leading up to a bodybuilding contest, as subcutaneous water retention (due to estrogen) can seriously lessen the look of hardness and definition to the muscles. Non-aromatizing steroids are therefore indispensable to the competitor, helping to bring about a tight, solid build the weeks leading up to a show. And of course without excess estrogen there is little chance of the athlete developing gynecomastia. Likewise there should never be a need for antiestrogen use with this steroid. Primobolan depot is also said to have a low impact on endogenous testosterone production. Although this may well be true in small clinical doses, it will not hold true for the bodybuilder. For example, in one stud more than half of the patients receiving only 30-45 mg noted a suppression of gonadotropin levels of 15% to 65% a. This is a dose far less than most bodybuilders would use, and no doubt increasing it would only lead to worse suppression. One would therefore still need a testosterone stimulating drug like HCG (Human Chorionic Gonadotropin) or Clomid/Nolvadex when concluding a low-dose Primobolan cycle, unless a deliberately small dose were being used